This paper presents a novel parallel implementation technology for wave-based structural health monitoring (SHM) in laminated composite plates. The wavelet-based B-spline wavelet on he interval (BSWI) element is constructed according to Hamilton’s principle, and the element by element algorithm is parallelly executed on graphics processing unit (GPU) using compute unified device architecture (CUDA) to get the responses in full wave field accurately. By means of the Fourier spectral analysis method,the Mindlin plate theory is selected for wave modeling of laminated composite plates while the Kirchhoff plate theory predicts unreasonably phase and group velocities. Numerical examples involving wave propagation in laminated composite plates without and with crack are performed and discussed in detail. The parallel implementation on GPU is accelerated 146 times comparing with the same wave motion problem executed on central processing unit (CPU). The validity and accuracy of the proposed parallel implementation are also demonstrated by comparing with conventional finite element method (FEM) and the computation time has been reduced from hours to minutes. The damage size and location have been successfully determined according to wave propagation results based on delay-and-sum (DAS). The results show that the proposed parallel implementation of wavelet finite element method (WFEM) is very appropriate and efficient for wave-based SHM in laminated composite plates. The wavelet presents a novel parallel implementation technology for wave-based structural health monitoring (SHM) in laminated composite plates. The wavelet-based B-spline wavelet on he interval (BSWI) element is constructed according to Hamilton’s principle, and the element by element algorithm is parallelly executed on graphics processing unit (GPU) using compute unified device architecture (CUDA) to get the responses in full wave field accurately. By means of the Fourier spectral analysis method, the Mindlin plate theory is selected for wave modeling of laminated composite plates while the Kirchhoff plate theory predicts unreasonably phase and group velocities. Numerical examples involving wave propagation in laminated composite plates without and with crack are performed and discussed in detail. The parallel implementation on GPU is accelerated 146 times comparing with the same wave motion problem on central processing unit (CPU). The validity and accuracy of the pro posed parallel implementation are also demonstrated by comparing with conventional finite element method (FEM) and the computation time has been reduced from hours to minutes. The damage size and location have been successfully determined according to wave propagation results based on delay-and-sum DAS). The results show that the proposed parallel implementation of wavelet finite element method (WFEM) is very appropriate and efficient for wave-based SHM in laminated composite plates.