心肌缺氧是心血管疾病中主要病因之一,为了加快寻找新的抗心肌缺氧药,建立简便易行的筛选方法十分必要。目前,抗心肌缺氧药物的筛选方法虽有多种,但有些方法特异性不高,有些方法要求较高的实验条件及操作技术,耗资较大,不宜于大量药物的筛选。本文报道一种操作简便、特异性高、耗资较少的筛选方法。 材料 动物:本校动物房自行繁殖的小鼠。 药物:心得安注射液 北京制药厂 批号 780606 潘生丁注射液 南京药学院制药厂 批 Myocardial hypoxia is one of the major causes of cardiovascular diseases. In order to speed up the search for new anti-myocardial oxygen drugs, it is necessary to establish a simple and convenient screening method. At present, there are many kinds of screening methods for anti-myocardial oxygen drugs, but some methods are not specific. Some methods require high experimental conditions and operation techniques, which are expensive and not suitable for screening large quantities of drugs. This article reports a simple, high specificity and less expensive screening method. Material animal: Our school animal room self-breeding mice. Drugs: Andean injection Beijing Pharmaceutical Factory Lot 780606 Dipyridamole Injection Nanjing Pharmaceutical Factory approved