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[问]氯喹啉和伯氨喹啉的用量都按其盐类中所含的基质计算,为什么要这样规定?基质是什么意思?直接按盐类计算用量有何不可?[答]氯喹啉本身是一种有机(?),它易于潮解和变质,必须与某些酸化合成盐类,化学性质才比较稳定。现在我国生产的氯喹啉只有磷酸盐一种,即磷酸氯喹啉,它含氯喹啉(?)(盐基)或称基质62.6%,进口货有硫酸盐和盐酸盐,硫酸氯喹啉含基质76.5%,盐酸氯喹啉则含基质90.0%,即三种氯喹啉盐类所含基质大不相同,而氯喹啉的抗瘧有效成份是它的基质,
[Q] The amount of chloroquine and primaquine are calculated according to the matrix contained in their salts, why should such a regulation? What is the meaning of the matrix? Calculated directly according to salt dosage? [A] chloroquine itself Is an organic (?), It is prone to deliquescence and metamorphism, must be combined with some acidification salts, chemical properties are relatively stable. Chloroquinoline produced in our country now has only one kind of phosphate, namely chloroquine phosphate, which contains chloroquine (?) (Base) or 62.6% of substrate, and imports of sulfates and hydrochlorides. Chloroquinoline sulfate has a substrate of 76.5 %, Chloroquine hydrochloride is 90.0% of the matrix, that is, the three quinoaquinoline salts contained in different substrates, and the active ingredient of chloroquine antimalarial is its matrix,