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目的 :探讨老年 2型糖尿病 (diabetesmellitus ,DM )患者微量白蛋白尿 (microalbuminuria ,MAU)、血脂、胰岛素 (Ins)水平变化及临床意义。方法 :对 3 0例健康对照老年人、5 6例老年 2型DM患者 ,其中 2 7例合并MAU和 2 9例未合并MAU患者进行血脂、空腹血糖 (FBG)、Ins水平等测定 ,并进行比较分析。结果 :老年 2型DM患者胆固醇 (TC)、甘油三酯 (TG)、低密度脂蛋白 -胆固醇 (LDL c)、载脂蛋白B(apoB)、FBG和Ins水平显著高于正常对照组 (P <0 .0 5 ) ,高密度脂蛋白 -胆固醇 (HDL c)和载脂蛋白A1(apoA1)则显著降低 ( P <0 .0 5 ) ;DM合并MAU组TG、Ins和糖化血红蛋白(HbA1c)显著高于无合并MAU组 (P <0 .0 5 )。结论 :说明血脂、微量白蛋白尿、胰岛素水平在老年 2型DM发展中起着重要作用。
Objective: To investigate the changes and clinical significance of microalbuminuria (MAU), serum lipids and insulin in elderly patients with type 2 diabetes mellitus (DM). Methods: Serum lipids, fasting blood glucose (FBG) and Ins levels were measured in 30 healthy controls and 56 elderly patients with type 2 DM, of which 27 were combined with MAU and 29 without MAU. comparative analysis. Results: The levels of cholesterol, triglyceride, LDLc, apoB, FBG and Ins in elderly type 2 DM patients were significantly higher than those in normal controls (P (P <0.05), TG, Ins and HbA1c in MAU group were significantly lower than those in control group (P <0.05), HDLc and apolipoprotein A1 (P0.05) Which was significantly higher than that of the non-combined MAU group (P <0.05). CONCLUSIONS: Lipid, microalbuminuria, and insulin levels play an important role in the development of type 2 DM in the elderly.