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目的了解鼻咽癌放射治疗后鼻窦炎患者筛窦黏膜的组织形态学结构。方法在光镜下观察15例鼻咽癌放疗后并发鼻窦炎患者的筛窦黏膜上皮层、基底层、固有层和小血管的组织形态学结构。结果鼻咽癌放疗后鼻窦炎患者的筛窦黏膜上皮明显脱落、萎缩,纤毛消失,细胞黏液化生,间质中广泛水肿、血管扩张,腺体大小不一、部分萎缩,炎性细胞浸润量少。结论鼻咽癌放疗后鼻窦炎患者的筛窦黏膜损伤严重,而放射性鼻窦炎的命名是否成立,有待于进一步研究。
Objective To understand the histomorphology of ethmoid sinus mucosa in patients with nasosinusitis after radiotherapy of nasopharyngeal carcinoma. Methods The morphological structures of the ethmoid epithelium, basal lamina, lamina propria and small vessels in 15 patients with nasopharyngeal carcinoma after radiotherapy were observed under light microscope. Results In the patients with nasopharyngeal carcinoma, the ethmoid epithelium of the patients with sinusitis were obviously detached, atrophic, ciliated disappeared, mucinous metaplasia, extensive edema in the interstitium, vasodilation, glandular size, partial atrophy and inflammatory cell infiltration less. Conclusion The mucosal damage of ethmoid sinus in patients with sinusitis after radiotherapy of nasopharyngeal carcinoma is serious, but whether the naming of radiological sinusitis is established remains to be further studied.