某些疱疹病毒可使人类罹患严重疾病,并且经常复发。保加利亚从1975年起把灭活疱疹疫苗应用于治疗实践。本文报告了此疫苗的效力和安全性。到1980年末止,共有2,350例患者接受免疫治疗。免疫后6个月期间,大约85％的患者有阳性应答,患者的病情有稳定好转的趋势,随着反复免疫接种,随访4～5年后,病人中有阳性应答者占95％以上。 Some herpes viruses can cause serious illness in humans and often recur. Bulgaria has been using heroin vaccines for therapeutic practice since 1975. This article reports the efficacy and safety of this vaccine. By the end of 1980, a total of 2,350 patients had received immunotherapy. About 6 months after immunization, about 85% of patients have a positive response, and the patient’s condition has a tendency of steady improvement. With repeated vaccinations, more than 95% of the patients have positive responses after 4 to 5 years of follow-up.