肼苯哒嗪可减少左室流出道阻力,从而增加心排出量和心搏量。用它治疗严重慢性充血性心力衰竭,可使许多患者获得显著改善。心衰病人对肼苯哒嗪需要量的变化很大,通常远远超过抗高血压疗法的用量。高血压病人一般用量≤50毫克即可收效,而心衰病人的单剂量如小于75毫克则很少显示血液动力学效应。本文45例心衰病人用肼苯哒嗪治疗,给药后体循环血管阻力明显减少(即较对照组减少20％以 Hydralazine can reduce left ventricular outflow tract resistance, thereby increasing cardiac output and stroke volume. Use it to treat severe chronic congestive heart failure, many patients can be significantly improved. Patients with heart failure on hydralazine requirements vary widely, usually far more than the amount of antihypertensive therapy. Hypertensive patients with a general dose of ≤ 50 mg can be effective, and a single dose of heart failure patients such as less than 75 mg rarely show hemodynamic effects. 45 cases of heart failure patients with hydralazine treatment, after administration of systemic vascular resistance was significantly reduced (ie, 20% reduction compared with the control group