婴儿死亡率中2/3死于新生儿期,而新生儿期中,尤以新生儿肺透明膜病(HMD)死亡率为高.肺透明膜病是由于缺乏肺表面活性物质(PS)引起,以早产儿为多见、近十年来,世界各地对PS研究蓬勃发展,用PS治疗HMD成功报道大幅度减少新生儿死亡率.本文观察25例新生儿肺透明膜病患儿进行检测胎龄、体重、APgar评分、L/S石及出现呼吸困难时间等项目提示:肺透明膜病发病与胎龄、WT、L/S(卵磷脂与鞘磷脂比例)呈正相关. Two-thirds of infant mortality is due to the neonatal period, especially in the neonatal period, especially in neonatal hyaline membrane disease (HMD), which is caused by a lack of pulmonary surfactant (PS) Premature babies are more common in the past decade, the vigorous development of PS research around the world, PS treatment of HMD successfully reported a significant reduction in neonatal mortality .This article observed 25 cases of neonatal hyaline membrane disease in children with gestational age, Body weight, APgar score, L / S stone, and time to breathing problems prompted hints of hyaline membrane disease and gestational age, WT, L / S (lecithin and sphingomyelin ratio) was positively correlated.