在口腔种植的诊疗过程中,常常由于缺牙区牙槽骨吸收,导致骨量不足而影响种植义齿修复效果的情况,这就需要利用自体骨或骨生物材料进行牙槽骨增量手术。常用的骨生物材料绝大多数为无机材料,基本不具有骨诱导作用,因此其效果有限。新型材料珍珠层来自于软体动物的贝壳内层,通常由95%碳酸钙和0.1%~5%的有机基质组成~([1])。虽然珍珠层无机成分与一般无机材料类似,但其中的有机成分却在骨诱导方面扮演着关键角色。 In the process of oral implant treatment, often due to alveolar bone loss in the tooth area, resulting in insufficient bone mass and affect the effect of implant prosthesis, which requires the use of autologous bone or bone material for alveolar bone augmentation surgery. The vast majority of commonly used bone biological materials for inorganic materials, the basic does not have osteoinduction, so its effectiveness is limited. The new material, nacre, comes from the inner shell of a mollusk shell and usually consists of 95% calcium carbonate and 0.1% to 5% organic matrix [1]. Although nacre inorganic components are similar to inorganic materials in general, the organic components play a key role in osteoinduction.