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目的:研究丹参注射液联合尿激酶治疗脑血栓的临床疗效。方法:选择我院2010年1月-2012年12月入住我院的脑血管疾病患者120例,平均分成观察组和对照组,两组患者一般资料比较无显著的统计学意义(P>0.05)。观察组在常规治疗的基础上给予20ml丹参注射液+250ml生理盐水静脉滴注,1次/d,14d为1疗程;给予0.5万U/kg+100ml生理盐水静脉滴注,滴注时间30min,14d为1疗程。对照组在常规治疗的基础上给予80mg奥扎格雷钠+250ml生理盐水静脉滴注,1次/d,14d为1疗程。结果:观察组治疗总有效率(100.00%)显著高于对照组总有效率(73.33%),两组患者总有效率比较,其结果存在着显著的统计学意义(p<0.01)。结论:丹参注射液联合尿激酶治疗脑血栓疗效显著,并发症、不良反应少,值得在临床上推广应用。
Objective: To study the clinical effect of Danshen injection combined with urokinase in the treatment of cerebral thrombosis. Methods: One hundred and twenty patients with cerebrovascular disease admitted to our hospital from January 2010 to December 2012 were divided equally into observation group and control group. There was no significant difference between the two groups (P> 0.05) . The observation group was given intravenous infusion of 20ml salvia miltiorrhiza injection + 250ml normal saline on the basis of routine treatment, once a day for 14 days for one course; intravenous drip of 0.5 million U / kg + 100ml normal saline for 30 minutes, 14d for a course of treatment. The control group was given 80mg ozagrel sodium + 250ml saline intravenously on the basis of routine treatment, once / d, 14d for a course of treatment. Results: The total effective rate (100.00%) in the observation group was significantly higher than that in the control group (73.33%). The total effective rate in the two groups was statistically significant (p <0.01). Conclusion: Danshen injection combined with urokinase in the treatment of cerebral thrombosis has obvious curative effect, less complications and fewer adverse reactions, which is worth popularizing in clinic.