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丙硫苯咪唑及其代谢物－两硫苯咪唑亚砜与丙硫苯咪唑砜１０ｍｇ／ｋｇ．Ｂｉｄ连续７日疗法，灌胃治疗大鼠实验感染的华支睾吸虫病。治后１周解剖，丙硫苯咪唑、丙硫苯咪唑亚砜及丙硫苯咪唑砜组的平均虫体回收数分别为０．４±０．７，０．２２±０．４４和１１．８±１０．４条。与对照组（１４．５±６．０条）比较．前二者有极显著的统计学差异，而后者则无。光镜观察经丙硫苯咪唑及其代谢物作用后的华支睾吸虫．可见虫体睾丸分支变细，失去正常形态，受精囊着色变浅，子宫内虫卵明显减少等变化。研究结果表明两硫苯咪唑亚砜是杀虫的主要成分，丙硫苯咪唑砜对抑制虫体排卵有一定作用。
Albendazole and its metabolites - diphenylsulfone and sulfamethoxazole sulfone 10mg / kg. Bid for 7 consecutive days of treatment, intragastric treatment of rat experimental infection Clonorchiasis. At 1 week after the treatment, the average number of recoveries of albendazole, albendazole and albendazole were 0.4 ± 0.7, 0.22 ± 0.44 and 11.8 ± 10.4, respectively. Compared with the control group (14.5 ± 6.0). The former two have very significant statistical differences, while the latter none. Observation by light microscope of propylthiophene and its metabolites of Clonorchis sinensis. Testicular branch of the worm can be seen thinning, loss of normal morphology, coloring shallow seminal vesicles, uterine eggs were significantly reduced and other changes. The results show that the two thiophanimic acid sulfoxide is the main component of insecticide, propylthiophene imidazole sulfone inhibition of parasites ovulation to a certain extent.