由于尼日利亚西南部抗氯喹恶性疟原虫的出现,需要在该地区对新抗疟药药效进行临床评价。本文报道用蒿甲醚治疗重症儿童急性恶性疟复燃的疗效。作者于1993年9月—1994年6月在尼日利亚伊巴丹大学医院收集符合下列标准的患儿进行研究:单纯性恶性疟、入院前24—48h内出现发热或其它疟疾症状、无法以口服途径用药、身体极度虚 Due to the emergence of Plasmodium falciparum in southwestern Nigeria, the clinical evaluation of the efficacy of the new antimalarial drug needs to be carried out in the area. This article reports the efficacy of artemether in the treatment of acute falciparum malaria in critically ill children. The study was conducted at the University of Ibadan Hospital in Nigeria from September 1993 to June 1994 with children who met the following criteria: Pure falciparum malaria, fever or other malaria symptoms within 24-48 hours prior to admission, no oral route Medication, the body extremely virtual