本文作者报道1例罕见的18号等臂双着丝粒染色体的男性患儿,核型为46,XY,idic(18)(p11.31→qter),经生物素标记的18号染色体探针原位杂交进一步证实。其临床表现类似于18三体综合征。细胞遗传学应用G带和Q带分析,已证实为18号染色体短臂部分单体和从p11.31→qter片段的三体。但患儿仅具有18号三体临床特征即:生长迟缓,低位耳、发育不全的耳廓,紧缩的小颌,紧握拳头,“摇椅” The authors report a case of a rare male eighteen male dicentric chromosome with a karyotype of 46, XY, idic (18) (p11.31 → qter), biotinylated chromosome 18 probe In situ hybridization further confirmed. Its clinical manifestations are similar to Trisomy 18. Cytogenetics Using G-band and Q-band analyzes, it has been demonstrated that the short arm partial 18 chromosome and the trisomy from the p 11.31 → qter fragment. However, only children with three trisomy 18 clinical features namely: growth retardation, low ears, hypoplasia ear, tight jaw, clenched fist, “rocking chair”