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锗是第32号化学元素,存在于土9357、动、植物中,常用于半导体工业。1973年日本报告锗~(132)有降压、免疫调节及抗肿瘤作用,1980年报告对乳腺癌,前列腺癌有效。但二氧化锗的造血作用已于1981年被否认。最近发现食用含锗食品可发生特异性肾损害。这种损害可在短期内发展为终末期肾功能不全(尿毒症)。作者将此疾病暂定名为二氧化锗肾病。其临床特点是食用含二氧化锗食品4～6个月出现肾功能不全,有时需短期透折治疗。停止食用后,肾损害继续进行,尿锗含量仍高,数年后肾损害持续存在。由于不出现最有特征的蛋白尿、血尿,因此常被漏诊。
Germanium is the 32nd chemical element found in soil 9357, animal and plant, commonly used in the semiconductor industry. 1973 Japan report germanium ~ (132) has antihypertensive, immunomodulatory and anti-tumor effect, the 1980 report on breast cancer, prostate cancer effective. But the hematopoiesis of germanium dioxide was denied in 1981. Recently found that consumption of foods containing germanium can occur specific renal damage. This damage can develop in the short term end-stage renal insufficiency (uremia). The author tentatively named the disease as germanium dioxide nephropathy. The clinical features of food containing germanium dioxide 4 to 6 months of renal insufficiency, and sometimes the need for short-term pass-through treatment. Stop eating, kidney damage continued, urinary germanium content is still high, a few years after the persistence of renal damage. Because it does not appear the most characteristic proteinuria, hematuria, so often missed.