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目的探索优化依沙吖啶中期引产的新方法。方法选择自愿彩用依沙吖啶引产的孕妇136例,在经腹羊膜腔穿刺注入依沙吖啶100㎎12小时后宫颈内放置米索前列醇0.1㎎,以后每隔6小时重复用药一次直至流产。结果136例孕妇全部在48小时内流产,平均流产时间为31.7小时,36小时内流产率达80.1%。平均出血量为58.9ml。药物副反应发生率低,仅有3例轻度恶心,10例轻度下腹痛。明显地缩短了引产流产时间,降低了药物副反应发生率,减轻了患者的痛苦。结论米索前列醇宫颈内给药用于依沙吖啶中期引产效果可靠,明显缩短了流产时间,副作用小。
Objective To explore a new method for optimizing midazolam induction of labor. Methods 136 cases of pregnant women induced by ethacridine were chosen voluntarily. After transabdominal amniocentesis was injected with ethacridine for 100 hours, misoprostol was placed in the cervix for 0.1 hours, and then repeated every 6 hours until abortion. Results All 136 pregnant women aborted within 48 hours. The average time for abortion was 31.7 hours and the abortion rate was 80.1% in 36 hours. The average amount of bleeding was 58.9ml. Low incidence of side effects of drugs, only 3 cases of mild nausea, 10 cases of mild abdominal pain. Obviously shortened the induction of abortion time, reducing the incidence of side effects of drugs, reducing the patient’s pain. Conclusion The misoprostol administered intracisternally is reliable for inducing midazolam mid-term induction, significantly shortening the time of abortion and having fewer side effects.