论文部分内容阅读
目的通过对有关宫腔镜应用与子宫内膜癌的临床对照研究资料进行荟萃分析(meta分析),探讨诊断性宫腔镜应用于早期子宫内膜癌患者后,是否会增加肿瘤细胞在腹水中的播散。方法检索1990年1月至2009年12月PUBME、EMBASE、中国生物医学文献数据库上公开发表的有关宫腔镜应用与子宫内膜癌和收集到的腹水或腹腔冲洗液中肿瘤细胞阳性或可疑阳性例数关系的文献,按照入选和排除标准,共有9篇临床对照试验纳入本研究,对其研究内容摘录后应用RevMan4.2软件进行分析。结果诊断性宫腔镜应用于子宫内膜癌患者后,与对照组比较有增加阳性腹水肿瘤细胞例数的风险,OR值为1.79,95%CI为(1.25,2.57)。结论根据现有的临床对照研究资料分析,宫腔镜可能增加子宫内膜癌肿瘤细胞的腹腔内播散,故宫腔镜推广应用于子宫内膜癌患者的诊断尚需谨慎。
Objective To investigate whether hysteroscopic diagnosis of hysteroscopy in patients with early endometrial cancer will increase the number of tumor cells in ascites after meta-analysis (meta-analysis) of clinical control data on hysteroscopy and endometrial cancer Dissemination. Methods A retrospective analysis was made on the relationship between hysteroscopy and endometrial cancer and the positive or suspicious positive tumor cells in ascites or peritoneal wash fluid collected from PUBME, EMBASE and China Biomedical Literature Database from January 1990 to December 2009. According to the inclusion and exclusion criteria, a total of 9 controlled trials were included in the study, and their contents were analyzed by RevMan 4.2 software. Results The diagnosis of hysteroscopy in patients with endometrial cancer, compared with the control group increased the number of cases of positive ascites tumor risk, OR was 1.79,95% CI (1.25,2.57). Conclusions According to the available clinical data, hysteroscopy may increase intraperitoneal dissemination of endometrial cancer cells. Therefore, the diagnosis of endometrial cancer should be treated with caution.