子宫肌壁间妊娠是一种罕见的异位妊娠,指妊娠物位于子宫肌壁,完全由子宫肌层环绕,与输卵管不相通,约占异位妊娠的1%,目前世界上文献报道仅50余例。肌壁间妊娠早期诊断困难,多因急腹症并发子宫破裂才得以诊断,近10余年来,由于超声技术的进步,更多的患者得以早期诊断,从而保留了患者的生育功能。本文报道了北京协和医院近3年收治的5例子宫肌壁间妊娠,现结合文献复习报道如下。一、临床资料例1 患者27岁,孕7产2,因清官术后阴道不规则出血4个月,外院化疗4个疗程于2005年6月13日入院。患者平素月经规律,末次月经2004年12月1日。2005年2月 Uterine muscle wall pregnancy is a rare ectopic pregnancy, refers to the pregnancy is located in the uterine muscle wall, completely surrounded by the myometrium, and tubal indifference, accounting for about 1% of ectopic pregnancy, the world reported only 50 Exceptions. Muscular wall early pregnancy diagnosis difficult, mostly due to acute abdomen complicated by uterine rupture was diagnosed in the past 10 years, due to advances in ultrasound technology, more patients can be diagnosed early, thus preserving the patient’s reproductive function. This article reports the Beijing Union Medical College Hospital in the past 3 years admitted to 5 cases of uterine muscle wall pregnancy, are now combined with the literature review reported below. First, the clinical data Example 1 patients 27 years old, 7 pregnant 2, due to irregular postoperative vaginal bleeding for 4 months, 4 courses of chemotherapy in the hospital on June 13, 2005 admission. Patients usually menstrual regularity, the last menstrual December 1, 2004. February 2005