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胃肠道间质瘤(gastrointestinal stromal tumor,GIST)是组织学上主要由梭形和/或上皮样细胞组成,免疫表型上普遍CDll7(KIT)阳性,遗传学上具有c-kit或血小板源性生长因子受体alpha(platelet-derived growth factor receptor alpha,PDGFRA)基因激活突变的最常见的胃肠道间叶源性
Gastrointestinal stromal tumors (GISTs) are histologically predominantly spindle and / or epithelial-like cells that are immunophenotypically prevalent on CDll7 (KIT), genetically c-kit or platelet-derived The most common gastrointestinal mesenchogenicity of the platelet-derived growth factor receptor alpha (PDGFRA) gene activation mutation