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根据维吾尔医学体液论,对305例维吾尔族冠心病患者进行异常体液分型分组,采用ELISA法,检测冠心病患者血浆可溶性细胞间黏附分子(sICAM-1)和可溶性血管细胞黏附分子(sVCAM-1)含量,观察不同异常体液型冠心病患者细胞黏附分子含量的变化,探讨细胞黏附分子在冠心病维吾尔医学异常体液分型中的临床意义。结果显示,305例维吾尔族冠心病患者中,异常黑胆质型冠心病70例、异常血液质型冠心病126例、异常胆液质型冠心病28例、异常黏液质型冠心病81例。与健康对照组比较,各组冠心病患者sICAM-1,sVCAM-1含量均有明显增加(P<0.01);在异常血液质组、异常胆液质组、异常黏液质组3组之间两两比较,均无显著性差异(P>0.05);但与其他3组进行两两比较,异常黑胆质组sICAM-1,sVCAM-1含量均高于其他各组(P<0.05)。这表明,不同异常体液型冠心病患者细胞黏附分子含量均发生异常变化,异常黑胆质型冠心病患者细胞黏附分子含量的异常变化较其他异常体液型冠心病患者更为严重。
According to the Uygur medical theory of body fluids, 305 cases of Uygur patients with coronary heart disease were divided into three groups according to the body fluids. ELISA and ELISA were used to detect the expression of soluble intercellular adhesion molecule (sICAM-1) and soluble vascular cell adhesion molecule (sVCAM-1) ) Content in patients with abnormal body fluid of coronary heart disease were observed in patients with changes in cell adhesion molecules, and to explore the clinical significance of cell adhesion molecules in the clinical abnormalities of Uyghur body fluid in patients with coronary heart disease. The results showed that in 305 Uighur patients with coronary heart disease, there were 70 cases of abnormal savda-type coronary heart disease, 126 cases of abnormal blood-type coronary heart disease, 28 cases of abnormal cholecystoid coronary heart disease and 81 cases of abnormal mucinous coronary heart disease. Compared with the healthy control group, the levels of sICAM-1 and sVCAM-1 in each group were significantly increased (P <0.01); in the group of abnormal blood group, abnormal bilirubin and abnormal mucinous group There was no significant difference between the two groups (P> 0.05). However, compared with other three groups, the levels of sICAM-1 and sVCAM-1 in the abnormal savda group were significantly higher than those in other groups (P <0.05). This shows that different abnormal body fluid coronary heart disease patients with abnormal changes in cell adhesion molecules, abnormal savda coronary heart disease patients with abnormal changes in cell adhesion molecules than other abnormal body fluid coronary heart disease patients more serious.