CONNEXIN相关论文
心脏起搏器治疗适应证已从病窦综合征等心脏传导系统疾病扩展到诸如治疗顽固性心力衰竭（心衰）、心室颤动（室颤）等非传导系统疾病[1,2]，......
糖尿病视网膜病变是糖尿病最常见的微血管并发症之一，也是一种常见的致盲性眼病。缝隙连接蛋白(connexin)介导的细胞间通信在维持视......
新生儿先天性听力损失是一种常见的出生缺陷。研究表明,新生儿听力损失发生率为0.1%～0.3%,重症监护病房的新生儿听力损失发生率可高......
目的 探讨人类连接蛋白基因 2 6 (connexin2 6 ,Cx2 6 )的调控机理。方法 对 Cx2 6基因转译起始点上游的一个 DNase- 1超敏区片......
目的了解中国人进行性腓骨肌萎缩症(Charcot-Marie-Tooth disease, CMT)连接蛋白32(connexin 32,Cx32)基因外显子2的突变情况.方法......
连接蛋白(connexin,Cx)是一类多基因家族表达的保守蛋白[1].6个Cx单体在细胞膜上环绕排列形成具有6角形中空结构的寡聚体蛋白,称连......
目的:观察通心络(Tongxinluo,TXL)超细干粉水提物对异丙肾上腺素(isoproterenol,Iso)诱导的H9c2心肌细胞肥大的作用,并探讨其对缝......
Vision altering diseases, such as glaucoma, diabetic retinopathy, age-related macular degeneration, myopia, retinal vasc......
OBJECTIVE To investigate the permeability of gap junction composed of connexin 43(Cx43)for micro RNAs(mi RNAs)and the im......
Non-junctional Cx32 mediates anti-apoptotic and pro-tumor effects via epidermal growth factor recept
OBJECTIVE To investigate the role of connexin proteins(Cx),which form gap junctions(GJ),in progression and chemotherapeu......
缝隙连接作为电突触的结构基础及相邻细胞间的通讯通道,近年来倍受关注,其主要组成蛋白——缝隙连接蛋白参与了多种疾病的发生发展......
目的通过观察高压氧(hyperbaric oxygen, HBO)对急性脊髓损伤(spinal cord injury, SCI)大鼠的受损脊髓组织血管内皮生长因子(vasc......
肌萎缩侧索硬化(ALS)是一种神经退行性疾病,其特征是中枢神经系统中运动神经元的进行性丧失.星形胶质细胞在ALS的疾病进程中起重要......
Cisplatin-induced premature senescence with concomitant reduction of gap junctions in human fibrobla
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Objective: To study the expression of connexin43 (Cx43) gene and its correlation with the apoptosis related genes Bcl-2 ......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Temporal dynamic changes of connexin 43 expression in C6 cells following lipopolysaccharide stimulat
Connexin 43, a gap junction protein, is expressed mainly in glia in the central nervous system.Neuroinflammation plays a......
目的 观察三七总皂苷(PNS)对B16黑色素瘤生长及转移的作用,及其对B16黑色素瘤表达缝隙连接蛋白Connexin32的影响.方法 实验采用B16......
Connexin subunits are proteins that form gap junction channels, and play an important role in communication between adja......
目的 观察c-Jun氨基末端激酶(JNK)-c-Jun通路对连接蛋白43(Cx43)表达的影响及在转化生长因子(TGF)β1诱导的肾小管上皮细胞-肌成纤......
Cisplatin-induced premature senescence with concomitant reduction of gap junctions in human fibrobla
To examine the role of gap junctions in cell senescence,the changes of gap junctions in cisplatin-induced premature sene......
