triptolide相关论文
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雷公藤内酯醇(triptolide),又称雷公藤内酯、雷公藤甲素,是从卫矛科雷公藤属雷公藤(tripterygium wilfordii Hook.F)、昆明山海棠[......
目的:以聚乙二醇单硬脂酸酯表面修饰材料结合到固体脂质纳米粒(solid lipid nanoparticles,SLN),以雷公藤内酯醇(triptolide,TPL)......
目的 探讨雷公藤内酯醇(TP)对人胰腺癌PANC1细胞株侵袭能力的影响及其与Toll样受体4/核因子-KB(TLR4/NF-KB)信号通路的关系.方法 ......
Effects of Triptolide on the Expression and Activity of NF-κB in Synovium of Collagen-induced Arthri
The expression and activity of NF-κB in the synovium of collagen-induced arthritis (CIA)rats was detected in order to i......
目的研究雷公藤内酯醇生物贴的体外经皮吸收特点。方法利用改良Franz扩散池研究雷公藤内酯醇生物贴的经皮吸收特点,以HPLC法测定雷......
Recent studies indicate that cell-cycle checkpoints are tightly correlated with the regulation of apoptosis, in which p5......
雷公藤内酯醇（triptolide）是从福建省泰宁县产的雷公藤根皮中分离提取的有效成分，我所经实验及临床Ⅰ、Ⅱ期研究发现其对多种髓系及淋......
目的研究雷公藤甲素自微乳对荷人前列腺癌PC-3细胞裸鼠移植瘤的抑制作用。方法构建荷人前列腺癌PC-3细胞裸鼠移植瘤,分为模型组、......
目的:建立高效液相色谱法测定复方雷公藤糖浆中雷公藤甲素的方法。方法:采用Diamonsil C18(150 mm×4.6 mm,5μm)色谱柱分离,甲醇-......
目的研究糖尿病大鼠肾皮质RANTES和desmin表达及雷公藤内酯醇对其干预作用。方法 SD大鼠随机分为正常组(NG)、模型组(DM)和小、大......
Effects of Triptolide on the Expression and Activity of NF-κB in Synovium of Collagen-induced Arthri
The expression and activity of NF-κB in the synovium of collagen-induced arthritis (CIA)rats was detected in order to i......
Relationship between Single Nucleotide Polymorphism in TNF-α Gene Promoter Region and Inhibitory Eff
The relationship between tumour necrosis factor-α (TNF-α) gene polymorphism and inhibitory effects of triptolide on TN......
Effect of Triptolide on Expression of Receptor Activator of Nuclear Factor-κB Ligand in Rat Adjuvant
The effect of triptolide (TP) on the expression of receptor activator of nuclear factor-κB ligand (RANKL) and osteoprot......
Objective Tripterygium wilfordii Hook. f. has been used for centuries in traditional Chinese medicine to treat autoimmun......
The Proteasomal Inhibitor MG132 Potentiates Apoptosis of Triptolide-Treated K562 Cells by Regulating
OBJECTIVE To explore the anticancer mechanism of triptolide in human leukemia K562 cells,and to further determine whethe......
目的研究雷公藤甲素(TP)对大鼠蛛网膜下腔出血(SAH)后的脑保护作用及其机制。方法48只雄性SD大鼠，在西安交通大学医学部动物实验中......
Astrocytes in an in vitro murine astrocyte model of oxygen and glucose deprivation/hypoxia and reoxygenation were treate......
目的 以抑癌基因即腺瘤性结肠息肉病相关基因(APE)存在异常甲基化的急性T淋巴细胞白血病Jurkat细胞为研究对象,探究雷公藤内酯醇(T......
目的 观察雷公藤甲素对2型糖尿病(T2DM)大鼠肾组织足细胞Nephrin、Podocin蛋白表达的影响及其机制探讨.方法 SPF级雄性8周龄Wistar......
Bootstrapping estimates of regression analysis for a non-random sample and its application in the re
Objective: To solve the problem of parameter estimate in the regression analysis of non-random sample. Methods: Calculat......
目的 研究雷公藤甲素洗脱支架抑制血管新生内膜增殖的有效性、对内皮功能的影响及支架安全性. 方法 将16只冠状动脉再狭窄模型小型......
This paper reviewed the study of triptolide-loaded nano delivery systems (NDOS) in our group during the past. It was inv......
Objective: To investigate the effects of triptolide tablet in the treatment of patients with psoriasis vulgaris. Methods......
目的 观察雷公藤多苷治疗糖尿病肾病(DN)Ⅲ期的疗效.方法 75例2型糖尿病并DNⅢ期患者,完全随机分为观察组(40例)和对照组(35例).观......
目的 观察厄贝沙坦联合雷公藤多甙对高原地区糖尿病肾病(DN)患者尿蛋白水平的影响.方法 将50例高原DN患者随机分为两组,对照组(25......
雷公藤内酯醇对多种非小细胞肺癌(non-small cell lung cancer,NSCLC)细胞系具有杀伤作用,可通过干预细胞周期、激活caspase信号通......
The long-term clinical efficacy of intracoronary stenting is limited by restenosis, which occurs in 15% to 30% of patien......
目的 探讨雷公藤甲素(TPT)预处理减轻小鼠肝脏缺血再灌注损伤的作用及其机制.方法 将C57BL/6小鼠随机分为4组(15只/组):假手术对照......
目的 通过体外实验研究雷公藤内酯醇(triptolide)对系统性红斑狼疮(systemic lupus erythematosus,SLE)患者树突状细胞(dendritic ......
目的 探讨IgA肾病(IgAN)患者外周血单个核细胞(PBMC)炎性因子分泌及自身凋亡状态,以及雷公藤甲素(TP)对其调节的相关机制.方法 取I......
目的 观察雷公藤甲素(TP)联合厄贝沙坦对2型糖尿病( T2DM)大鼠足细胞损伤的协同保护作用,并探讨其机制.方法 实验分为正常对照组(N......
Triptolide-induced Apoptosis by Inactivating Nuclear Factor-kappa B Apoptotic Pathway in Multiple My
The effect of triptolide on proliferation and apoptosis of human multiple myeloma RPMI-8226 cells in vitro,as well as th......
目的 探讨雷公藤甲素(TPT)预处理减轻小鼠肝脏缺血再灌注损伤的作用及其作用机制.方法 将60只雄性C57BL/6小鼠分成4组,每组15只.(1......
The Proteasomal Inhibitor MG132 Potentiates Apoptosis of Triptolide-Treated K562 Cells by Regulating
OBJECTIVE To explore the anticancer mechanism of triptolide in human leukemia K562 cells,and to further determine whethe......
目的观察雷公藤内酯醇(Tri)对实验性自身免疫性脑脊髓炎(EAE)小鼠小胶质/巨噬细胞极化的影响。方法60只SJL/J小鼠随机分为对照组、......
