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将我院2012年10月~2014年10月收治的114例急性脑出血患者,随机分为两组各57例。对照组用常规治疗方案治疗,观察组常规治疗方案加用依达拉奉和尼莫地平进行治疗。对比两组患者治疗后临床疗效以及脑血肿和水肿体积的变化情况。结果观察组总有效率84.21%高于对照组(P<0.05);两组治疗后血肿体积、水肿体积均显著小于治疗前(P<0.05),且观察组治疗后血肿体积、水肿体积均显著小于对照组(P<0.05)。依达拉奉联合尼莫地平可通过不同的机制协同改善急性脑出血患者继发性脑水肿,提高临床治疗效果。
114 patients with acute cerebral hemorrhage admitted from October 2012 to October 2014 in our hospital were randomly divided into two groups of 57 cases each. The control group was treated with conventional treatment regimen and the observation group with conventional regimen plus edaravone and nimodipine. The curative effect and the change of cerebral hematoma and edema volume were compared between the two groups after treatment. Results The total effective rate in the observation group was 84.21% higher than that in the control group (P <0.05). The hematoma volume and edema volume in both groups were significantly lower than those before treatment (P <0.05), and the hematoma volume and edema volume in the observation group were significantly Less than the control group (P <0.05). Edaravone combined with nimodipine can synergistically improve secondary cerebral edema in patients with acute cerebral hemorrhage through different mechanisms and improve clinical curative effect.