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天然人白细胞干扰素制剂在小鼠细胞内并无明显活性。然而重组型人白细胞干扰素(RHLI)α D(亚型)和αA/D(杂交型)在培养的小鼠细胞内和在小鼠体内均有较强的活性。人羊膜(FL)单细胞培养层吸附脑心肌炎病毒前24小时加入RHLIαA/D,使蚀斑形成减少50％
Natural human leukocyte interferon preparations did not show significant activity in mouse cells. However, recombinant human leukocyte interferon (RHLI) α D (subtype) and αA / D (hybrid) are highly active in cultured mouse cells and in mice. Addition of RHLIαA / D 24 hours prior to adsorption of encephalomyocarditis virus in human amniotic membrane (FL) single cell culture layer reduced plaque formation by 50%