目的 :了解一氧化氮 (NO)、左旋精氨酸 (L -Arg)、氨茶碱对急性高原病的治疗情况 ;方法 :利用右心漂浮导管法对急性缺氧幼猪应用NO、L -Arg、氨茶碱后血流动力学及血气的变化情况进行观察 ;结果 :急性缺氧幼猪应用NO、L -Arg、氨茶碱后 ,各组自身前后比较 ,肺血管阻力 (PVR)、肺动脉平均压 (mPAP)均显著降低 ,SaO2 、PaO2 显著升高 (P <0 .0 0 1～ 0 .0 5) ,其中以NO的改变幅度最大 ;结论 :NO、L -Arg、氨茶碱均能显著降低急性缺氧幼猪的肺动脉压 ,提高SaO2 ,其中以NO效果最好 Objective: To investigate the treatment of acute altitude sickness by nitric oxide (NO), L-arginine (L-Arg) and aminophylline.Methods: The acute hypoxia piglets were treated with NO, L - Arg, aminophylline and hemodynamics were observed. Results: After application of NO, L-Arg and aminophylline in acute hypoxia-treated pigs, the pulmonary vascular resistance (PVR) The mean pulmonary arterial pressure (mPAP) was significantly decreased, SaO2 and PaO2 were significantly increased (P <0.001. 0 5), of which NO was the largest change; Conclusion: NO, L- Arg, Can significantly reduce the pulmonary hypoxia in acute hypoxia, increase SaO2, of which the best NO effect