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目的:探讨临床治疗慢性阻塞性肺病合并呼吸衰竭的有效途径。方法:选取50例慢性阻塞性肺病合并呼吸衰竭患者为研究对象,将其随机分为两组,其中实验组30例,对照组20例。两组均给予鼻导管吸氧、抗感染、平喘祛痰、平衡水电解质、支气管扩张等常规性治疗,实验组在此基础上加用无创呼吸机治疗,观察比较两组的临床治疗效果。结果:经过治疗,两组患者的动脉血氧分压明显升高,二氧化碳分压、心率、呼吸频率均下降,与治疗前比较差异显著,且实验组患者症状改善情况显著优于对照组,差异具有统计学意义(P<0.05);两组中转气管插管和死亡人数比例、住院时间比较差异均具有统计学意义(P<0.05)。结论:在常规治疗的基础上应用无创呼吸机正压通气治疗慢性阻塞性肺病合并呼吸衰竭可提高患者生存率,大大改善患者生活质量,具有较高的临床应用价值。
Objective: To explore the clinical treatment of chronic obstructive pulmonary disease with respiratory failure effective ways. Methods: Fifty patients with chronic obstructive pulmonary disease and respiratory failure were selected as study subjects and randomly divided into two groups, 30 in experimental group and 20 in control group. The two groups were given nasal catheter oxygen, anti-infective, asthma and expectorant, balance of water and electrolyte, bronchiectasis and other conventional treatment, the experimental group on this basis with noninvasive ventilator treatment, observation and treatment of the two groups were compared. Results: After treatment, the partial pressure of arterial oxygen in both groups increased significantly, the partial pressure of carbon dioxide, heart rate and respiratory rate decreased significantly compared with those before treatment, and the improvement of symptoms in experimental group was significantly better than that in control group (P <0.05). The proportion of tracheal intubation and death and the length of hospital stay in both groups were statistically significant (P <0.05). Conclusion: The application of noninvasive ventilator positive pressure ventilation on chronic obstructive pulmonary disease combined with respiratory failure can improve the survival rate of patients on the basis of routine treatment, greatly improve the quality of life of patients with high clinical value.