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近年来,随着纤维胃镜技术的开展,人们发现慢性肝病,尤其是肝硬化病人常合并有溃疡病与慢性胃炎。几乎所有肝病患者都存在不同程度的胃粘膜损害。肝硬化合并胃溃疡的发生率比普通人高2倍;乙肝病毒表面抗原阳性者并胃溃疡的发病率达33％。 为何慢性肝病、肝硬化病人比较容易患胃溃疡与慢性胃炎呢?其原因有许多。一是因为肝功能不良,对组织胺、5-羟色胺等化学物质的灭活能力降低,由于肝硬化后侧枝循环形成,这类物质可不经肝脏直接进入血液循环,并使胃酸分泌增加,造成胃粘
In recent years, with the development of fiber endoscopy, it was found that chronic liver disease, especially patients with liver cirrhosis often associated with ulcer disease and chronic gastritis. Almost all patients with liver disease have varying degrees of gastric mucosal damage. The incidence of liver cirrhosis with gastric ulcer 2 times higher than the average person; hepatitis B virus surface antigen-positive and gastric ulcer incidence rate of 33%. Why chronic liver disease, liver cirrhosis patients are more susceptible to gastric ulcer and chronic gastritis? There are many reasons. First, because of poor liver function, on histamine, serotonin and other chemical substances decreased inactivation capacity, due to the formation of cirrhosis collateral circulation, these substances can be directly into the blood circulation without the liver, and to increase gastric acid secretion, resulting in stomach stick