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本文检测了放置改良Nova—T型LNG-Cu-IUD妇女的肝肾功能及代谢有关指标,为长期使用安全性提供依据。 一、对象和方法 采用前瞻性研究,观察健康育龄妇女放置LNG-Cu-IUD前及置器后3个月、6个月及18个月血液若干生化指标的变化。LNG-Cu-IUD为日释10.8μgLNG、铜丝面积220 mm~2、以医用聚乙烯为支架材料的Nova-T型宫内节育器,受试对象18名,年龄25～33岁,体重正常,无糖尿病、肥胖家族史、肝病史及吸烟、嗜酒等习惯,近期内未用过甾体激素
This article examines the placement of improved Nova-T-type LNG-Cu-IUD liver and kidney function and metabolism of related indicators, provide the basis for long-term use of safety. First, the object and method A prospective study was conducted to observe the changes of several biochemical markers of blood at 3 months, 6 months and 18 months after placement of LNG-Cu-IUD and placement device in healthy women of childbearing age. The LNG-Cu-IUD is a Nova-T intrauterine device with a surface area of 220 mm ~ 2 and a surface area of 10.8 μgLNG on a daily basis. Eighteen patients aged 25-33 years old with normal body weight , No diabetes, obesity family history, history of liver disease and smoking, alcohol and other habits, the recent use of steroid hormone