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目的:探讨糖尿病合并干酪性肺炎患者应用小剂量糖皮质激素治疗的临床疗效与价值。方法:选取本院54例糖尿病合并干酪性肺炎患者作为研究对象,根据不同治疗方案随机分2组,27例患者采用常规抗痨及控制血糖等治疗,将其定为对比组,27例患者应用小剂量糖皮质激素进结合常规治疗,将其定为观察组。观察各组患者血糖、肺部病灶等情况并比较疗效。结果:观察组肺部病灶吸收率(66.7%)及血糖均高于对比组(P<0.05),观察组与对比组痰菌转阴率相较P>0.05无明显差异。结论:糖尿病合并干酪性肺炎患者予以小剂量糖皮质激素治疗虽可导致患者血糖偏高但不影响痰菌转阴,患者肺部病灶吸收快,应用时间短且无明显全身并发症,具有较高安全性及可行性。
Objective: To investigate the clinical efficacy and value of low dose glucocorticoid therapy in diabetic patients with caseous pneumonia. Methods: 54 patients with diabetes mellitus complicated with caseous pneumonia in our hospital were selected as study subjects. Patients were randomly divided into two groups according to different treatment regimens. Twenty-seven patients were treated with conventional anti-tuberculosis and blood glucose control, which were compared with 27 patients Small doses of glucocorticoids combined with conventional treatment, will be set as the observation group. Observe the blood glucose, lung lesions and other conditions in each group and compare the curative effect. Results: The lung lesions absorption rate (66.7%) and blood glucose in the observation group were higher than those in the control group (P <0.05). There was no significant difference between the observation group and the control group in the negative conversion rate of sputum bacteria. Conclusion: Small doses of glucocorticoid therapy in patients with diabetes mellitus complicated with pneumonia of the pneumonia may lead to high blood glucose but not to negative conversion of sputum bacteria. The lung lesions of patients with diabetes mellitus are absorbed fast, with short application time and no obvious systemic complications, with high Safety and feasibility.