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为探讨肥大细胞在慢性肝病中的作用，应用甲苯胺蓝染色和免疫组化染色观察５０例人肝组织中肥大细胞与储脂细胞的密度和分布特征。结果显示慢性肝病组肥大细胞与储脂细胞密度都有增加，各自与正常肝组织相应指标比较差异有显著性（Ｐ＜００５），且二者在数量的增加程度方面呈正相关（γ＝０８２），分布以结缔组织区域多见。提示肥大细胞可能在慢性肝病的发展过程中起重要作用
To investigate the role of mast cells in chronic liver disease, the density and distribution characteristics of mast cells and fat-storing cells in 50 human liver tissues were observed by toluidine blue staining and immunohistochemical staining. The results showed that the density of mast cells and fat-storing cells in chronic liver disease group were increased, and there was significant difference between them (P <005) and normal liver tissue (P <005) 0 82), the distribution of connective tissue more common. Tip mast cells may play an important role in the development of chronic liver disease