患者男,72岁,因精神错乱、恶心和全身无力入院。有晚期肾病史,1月前因银屑病泛发而外用含10%水杨酸复方霜剂、每日3次涂于约占80%体表的皮损区,持续用药3～4周。入院体检:血压90/60mmHg、脉博100次/分、口温38.5℃、呼吸30次/分,面部、躯干和四肢分布融合性斑块型。实验室血清检查:钠142mmol/L、钾6.0mmol/L、氯102mmol/L、CO_215mmol/L,尿素氮25mmol/L、白蛋白34g/L;动脉血气 Male, 72 years old, admitted to hospital due to insanity, nausea and general inability. A history of advanced kidney disease, 1 month ago due to pan-psoriasis and topical application of 10% salicylic acid compound cream, 3 times a day applied to about 80% of the body surface lesions, continued medication for 3 to 4 weeks. Admission medical examination: blood pressure 90 / 60mmHg, pulse Bo 100 / min, mouth temperature 38.5 ℃, breathing 30 beats / min, facial, trunk and limb distribution fusion plaque type. Laboratory serum tests: sodium 142mmol / L, potassium 6.0mmol / L, chlorine 102mmol / L, CO_215mmol / L, urea nitrogen 25mmol / L, albumin 34g / L;