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报告经腹腔镜ＣＯ２激光卵巢打孔治疗难治性多囊卵巢综合征（ＰＣＯＤ）２０例。术后８例患者自然排卵，１１例患者用克罗米芬治疗有排卵。８例患者术后妊娠，１例孕６周自然流产，７例目前在妊娠中，妊娠率为４０％。流产率为１２．５％。术后血中睾酮及促黄体生成素（ＬＨ）浓度明显下降，而促卵泡生成素（ＦＳＨ）浓度改变不明显。术后激素环境改变是诱发排卵的主要机理。ＣＯ２激光具有作用部位准确，组织破坏程度易控制及手术野无出血等优点。本治疗具有损伤小，恢复快的特点。一次治疗可获多个排卵周期，无多胎妊娠及卵巢过度刺激综合征等合并症，是治疗难治性ＰＣＯＤ的有效方法。
The report of laparoscopic CO2 laser ovarian perforation treatment of refractory polycystic ovary syndrome (PCOD) in 20 cases. Eight patients had ovulation spontaneously and 11 patients had ovulation with clomiphene. Eight patients had postoperative pregnancy, 1 had spontaneous abortion at 6 weeks of pregnancy, and 7 had pregnancy at present with a pregnancy rate of 40%. Abortion rate was 12.5%. Postoperative serum testosterone and luteinizing hormone (LH) concentrations decreased significantly, while follicle stimulating hormone (FSH) concentration did not change significantly. Postoperative changes in hormone environment is the main mechanism induced ovulation. CO2 laser with the role of site accuracy, easy to control the extent of tissue damage and surgical field without bleeding and so on. The treatment has the characteristics of small damage, fast recovery. A treatment can be multiple ovulation cycles, no multiple pregnancies and ovarian hyperstimulation syndrome and other complications, is an effective method for the treatment of refractory PCOD.