最新研究提示,所有结肠癌患者术后都应进行Lynch综合征检查以确定是否患有携带高风险癌症的遗传性综合征。2%～3%的结肠癌患者可能携带遗传性变异基因,即Lynch综合征,亦可称为遗传性非息肉结肠癌(HNPCC)。研究人员认为,对Lynch综合征的筛查有助于患者获得相关的遗传学信息咨询和检测以鉴别是个体发病或家族性疾病;此外,检测还可帮助医生准确评估患者的长期预后。来自于美国俄亥俄州立大学综合癌症研究中心的Arthur G.James肿瘤医院和Richard J.Solove研 Recent research suggests that all patients with colon cancer should undergo a Lynch syndrome checkup to determine if they have a hereditary syndrome that carries high-risk cancers. 2% to 3% of colon cancer patients may carry a heritable genetic variant, Lynch syndrome, also known as hereditary nonpolyposis colon cancer (HNPCC). Researchers believe that screening for Lynch syndrome can help patients obtain relevant genetic information counseling and testing to identify individuals with disease or familial disease; in addition, the test can help doctors accurately assess the patient’s long-term prognosis. Arthur G. James Tumor Hospital from the Ohio State University Comprehensive Cancer Center and Richard J. Solove Research