糖尿病患者单发的颅神经病主要侵犯动眼神经和外展神经,常伴有眼球疼痛,有时呈周期性发作。在少数尸解病例中可观察到病灶性局部缺血,可认为是引起脱髓鞘神经损害的原因。精尿病并发双侧多发的颅神经麻痹以往曾有少数报导,但均缺乏病理材料,本文报告1例表现为双侧动眼神经麻痹的多发性神经病并经病理资料证实。患者,女性,72岁,患有Ⅱ型糖尿病,主诉突然出现复视和眼球疼 Cranial neuropathy of diabetes mellitus patients mainly affects the oculomotor nerve and abducens nerve, often accompanied by pain in the eye, and sometimes cyclical attacks. In a small number of autopsy cases can be observed in focal ischemia, can be considered to cause demyelination nerve damage. In the past, there were a few reports of cranial nerve palsy complicated by both-side and both-side disease in the past. However, all of them lack pathological materials. One case of this disease was reported as polyneuropathy with bilateral oculomotor nerve palsy and confirmed by pathological data. Patient, female, age 72, suffering from type 2 diabetes mellitus, complains of sudden diplopia and eyeball pain