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牙周膜是牙骨质与牙槽骨之间的致密纤维结缔组织。人牙周膜细胞是一类具有异质性及分化潜能的细胞,主要存在四种类型的细胞:结缔组织细胞、malassez上皮剩余细胞、防御细胞以及与神经、血管相关的细胞[1]。人牙周膜成纤维细胞是牙周膜中的主要细胞,具有更新和修复的能力,在牙周膜的生理与病理过程中具有重要的意义[2]。近年来,许多学者就牙周膜体外培养进行了大量的研究,并做出了一
Periodontal ligament is a dense fibrous connective tissue between cementum and alveolar bone. Human periodontal ligament cells are a group of cells with heterogeneity and differentiation potential. There are mainly four types of cells: connective tissue cells, remaining cells of malassez epithelium, defensive cells, and neural and vascular related cells [1]. Human periodontal ligament fibroblasts are the main cells in the periodontal ligament, which have the ability of renewal and repair, which is of great significance in the process of periodontal ligament physiology and pathology [2]. In recent years, many scholars on the periodontal ligament in vitro culture conducted a lot of research and made a