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环孢素A(CsA)是目前器官移植及治疗其他免疫性疾病广泛使用的免疫抑制剂,但CsA引起的肾脏损害近几年明显增多。本文就CsA的肾毒性及其防治的研究进展作了简要综述。
Cyclosporine A (CsA) is the most widely used immunosuppressant for organ transplantation and other immune diseases. However, CsA-induced renal damage has been significantly increased in recent years. This article reviews the progress of renal toxicity of CsA and its prevention and treatment.