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目的评价甲氨蝶呤联合米非司酮治疗异位妊娠的临床效果。方法本研究以我院2012年1月至2013年11月收治的100例异位妊娠患者为研究对象,随机将其分为两组,对照组仅接受甲氨蝶呤治疗,试验组接受甲氨蝶呤联合米非司酮治疗,对比分析两组患者的临床疗效。结果试验组患者临床治愈率、包块消失时间、血清人绒毛膜促性腺激素(β-HCG)转阴时间、治疗7d血β-HCG降低15%比例等指标明显优于对照组(P<0.05),两组患者治疗前血β-HCG水平对比差异无统计学意义(P>0.05)。结论甲氨蝶呤联合米非司酮治疗异位妊娠效果优于单用甲氨蝶呤。
Objective To evaluate the clinical efficacy of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods In this study, 100 cases of ectopic pregnancy treated in our hospital from January 2012 to November 2013 were randomly divided into two groups. The control group received methotrexate only. The experimental group received methotrexate Pterin combined with mifepristone treatment, comparative analysis of two groups of patients with clinical efficacy. Results The clinical cure rate, disappearance of mass, disappearance time of serum human chorionic gonadotropin (β-HCG) and 15% reduction of blood β-HCG on the 7th day were significantly better than those of the control group (P <0.05 ). There was no significant difference in β-HCG levels between the two groups before treatment (P> 0.05). Conclusion Methotrexate combined with mifepristone treatment of ectopic pregnancy better than methotrexate alone.