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目的观察绝经取环术中联合应用米索前列醇以及利多卡因的临床效果。方法选取医院收治的绝经取环术患者90例随机分为观察组和对照组,每组45例。对照组采用常规取环术,观察组术前2~3 h在阴道后穹窿处放置米索前列醇400μg,术中采用利多卡因注射,取环术同对照组。观察2组患者宫颈软化效果、取环效果以及疼痛情况。结果观察组宫颈软化率为84.4%,高于对照组的66.7%(P<0.05);观察组取环成功率为95.6%,高于对照组的82.2%(P<0.05);观察组患者疼痛率为28.9%,低于对照组的66.7%(P<0.01)。结论绝经取环术中联合应用利多卡因以及米索前列醇有利于促进宫颈扩张,缓解妇女疼痛,提高取环成功率,是一种操作简便、安全有效的用药方案。
Objective To observe the clinical effect of combined misoprostol and lidocaine in menopause. Methods Ninety cases of postmenopausal patients who were admitted to hospital were randomly divided into observation group and control group, with 45 cases in each group. In the control group, conventional misoprostol was used. In the observation group, misoprostol (400μg) was placed in the posterior vaginal fornixes 2 ~ 3 hours before surgery. Lidocaine was injected intraoperatively in the vaginal fornix and the control group. Cervical softening effect, loop effect and pain were observed in two groups. Results The cervix softening rate in the observation group was 84.4%, which was higher than that in the control group (66.7%, P <0.05). The success rate of taking the ring in the observation group was 95.6%, higher than that in the control group (82.2%, P <0.05) The rate was 28.9%, lower than 66.7% of the control group (P <0.01). Conclusions Combination of lidocaine and misoprostol in postmenopausal circumcision is helpful to promote cervical dilatation, relieve the pain of women and improve the success rate of fetching ring. It is a safe, effective and convenient medication regimen.