随着生物医药技术的发展 ,越来越多的多肽蛋白药物得到研究开发并应用于临床 ,同时也给药物制剂带来新挑战。由于多肽和蛋白药物的不稳定和易变质 ,将其制成稳定、安全和高效的药物制剂是一项复杂艰巨的工作。目前对于多肽蛋白药物的给药系统进行了大量的研究 ,已有用于不同的 With the development of biomedical technology, more and more peptide and protein drugs have been researched and developed and applied to clinical applications, which also bring new challenges to pharmaceutical preparations. Due to the instability and perishability of peptides and protein drugs, making them stable, safe and efficient pharmaceutical preparations is a complex and daunting task. Numerous studies have been conducted on the delivery system of the peptide protein drugs, which have been used for different