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目的 探讨脑白质疏松（ Ｌ Ａ） 对老年人认知功能的影响。方法 对３０ 名有 Ｌ Ａ 无精神神经病史及体征的老年人，３０ 名无 Ｌ Ａ 的腔隙性脑梗死患者及３０ 名正常老年人，用老年认知功能量表评定认知功能，并查听觉事件相关电位，还探讨年龄、脑血管疾病危险因素和 Ｌ Ａ 的关系。结果 有 Ｌ Ａ 老人的空间结构能力得分比腔梗病人、正常老人减低， Ｌ Ａ 程度与分析及综合能力、短时记忆及其保存能力呈负相关。腔梗病人的 Ｐ３ 潜伏期比正常老人明显延长。年龄和 Ｌ Ａ 程度呈正相关，有 Ｌ Ａ 老人的高血压患病率比正常老人明显高。结论 老年人的 Ｌ Ａ 对其认知功能有损害，以空间结构能力、精细操作技能较明显。高龄、高血压是 Ｌ Ａ 发生的危险因素。
Objective To investigate the effect of leucopenia (L A) on cognitive function in the elderly. Methods Thirty elderly patients with L A neuropsychiatric history and signs, 30 lacunar infarction patients without L A and 30 normal controls were enrolled in this study. The cognitive function was assessed by the Elderly Cognitive Function Scale Auditory event-related potentials, but also explore the relationship between age, risk factors of cerebrovascular disease and L A. The results showed that the spatial structure ability score of elderly people with L A was lower than that of the elderly patients and the normal elderly patients. The level of L A was negatively correlated with the ability of analysis and comprehensive ability, short-term memory and their preservation ability. The laryngeal infarction patients with P3 latency was significantly longer than normal. There was a positive correlation between age and L A level. The prevalence of hypertension in L A elderly was significantly higher than that in normal elderly. Conclusion L A in the elderly is impaired in cognitive function, with obvious spatial structure and fine operation skills. Elderly, hypertension is a risk factor for L A.