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目的监测健康人群麻疹抗体水平,提高实验室监测工作质量,为消除麻疹提供科学依据。方法麻疹IgM和IgG测定用ELISA方法,病原学检测按WHO推荐方法进行。结果河北省2012年麻疹实验室检测疑似麻疹病例血清标本814人份,麻疹IgM抗体阳性16例,阳性率1.97%;同时检测风疹IgM抗体814例,阳性123例,阳性率15.11%。2012年44人份咽拭子标本中分离出1株麻疹病毒,经核苷酸序列分析鉴定,为H1a基因型。结论实验室监测是麻疹监测系统的重要组成部分,对消除麻疹和控制风疹工作发挥着重要作用。河北省目前存在本土麻疹病毒的传播,以散发为主,人群免疫力水平较高。
Objective To monitor the level of measles antibody in healthy population, improve the quality of laboratory monitoring and provide a scientific basis for eliminating measles. Methods measles IgM and IgG determination by ELISA method, etiological detection according to WHO recommended methods. Results 814 measles cases were detected by measles laboratory in Hebei Province in 2012, and 16 cases were positive for measles IgM antibody. The positive rate was 1.97%. 814 cases of rubella IgM antibody were positive, of which 123 cases were positive. The positive rate was 15.11%. In 2012, 44 cases of throat swab specimens were isolated from a measles virus identified by nucleotide sequence analysis for the H1a genotype. Conclusion Laboratory monitoring is an important part of the measles monitoring system and plays an important role in eliminating measles and controlling rubella. Hebei Province, there is the spread of the local measles virus, mainly to the distribution, the crowd a higher level of immunity.