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目的通过2型糖尿病白内障围手术期胰岛素泵治疗前后糖化血清蛋白(GSP)变化,明确GSP在短期血糖控制中的作用,探讨其临床应用价值。方法选择2008-01-2010-02住院32例行糖尿病白内障手术患者。术前、术后测定空腹血糖、餐后2 h血糖、糖化血红蛋白(HbA1c)、白蛋白。结果 GSP水平术后均明显低于术前(P值<0.05),治疗前后HbA1c比较无显著变化。结论 GSP可准确、及时地反映短期内平均血糖控制水平,比HbA1c更适合作为短期降糖疗效监测指标。
Objective To investigate the role of GSP in short-term glycemic control by the changes of glycosylated serum protein (GSP) before and after treatment of type 2 diabetic cataract with insulin pump and to explore its clinical value. Methods 2008-01-2010-02 hospitalized 32 patients with diabetes cataract surgery. Preoperative and postoperative fasting blood glucose, postprandial blood glucose 2 h, HbA1c, albumin. Results The levels of GSP were significantly lower than those before operation (P <0.05). There was no significant change in HbA1c before and after treatment. Conclusion GSP can accurately and timely reflect the average blood glucose control level in the short term, which is more suitable than HbA1c as a monitoring indicator of short-term hypoglycemic effect.