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我院自1999年10月～2002年2月应用小剂量尿激酶治疗进展型脑血栓40例,取得了满意的疗效,现报道如下: 1 临床资料 1.1 病例选择:80例均为住院病人,全部为急性期病例,发病后肌力进行性下降,发病72小时内就诊,肌力0～Ⅲ级,年龄<75岁,均经颅脑CT确诊,按入院先后顺序随机分成两组:治疗组40例,男22例,女18例;对照组40例,男26例,女14例。除外溶栓药物禁忌症者,如出血倾向及有出血性卒中病史等,深昏迷及大面积梗塞者不选入。
Our hospital from October 1999 to February 2002 application of low-dose urokinase in the treatment of progressive cerebral thrombosis in 40 cases, and achieved satisfactory results are reported as follows: 1 Clinical data 1.1 Case Selection: 80 cases were hospitalized patients, all For acute cases, the onset of muscle strength decreased, within 72 hours of onset of treatment, muscle strength 0 ~ Ⅲ grade, age <75 years old, were confirmed by brain CT, according to admission sequence were randomly divided into two groups: treatment group 40 Cases, 22 males and 18 females; control group 40 cases, 26 males and 14 females. Excluding thrombolytic drugs contraindications, such as bleeding tendency and a history of bleeding stroke, deep coma and large infarcts were not selected.