慢性乙型肝炎病毒(hepatitis B virus,HBV)感染是慢性传染性疾病,具有传染性、难治性、病程长及费用高、预后反应不良特点,患者在就业和择业方面易受到歧视,需要承受较大的心理负担,易导致抑郁症的发生[1-3],不仅因为治疗的依从性降低影响躯体疾病的治疗效果,而且还会因为严重心理障碍产生自杀倾向,形成社会问题[4]。为了解慢性HBV感染患者的抑郁情况,本研究于2013年9月在辽宁 Chronic hepatitis B virus (HBV) infection is a chronic infectious disease that is contagious, refractory, long-lasting and costly, and has a poor prognosis. Patients are vulnerable to employment and career discrimination and need to bear The larger psychological burden easily leads to the occurrence of depression [1-3], not only because treatment compliance reduces the treatment effect of somatic diseases, but also causes suicide tendency due to serious psychological disorder, which leads to social problems [4]. To understand the depression in patients with chronic HBV infection, this study was conducted in Liaoning in September 2013