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进展期宫颈癌局部放疗失败的主要原因有原发灶巨大、肿瘤绝对剂量不足和基因学改变导致肿瘤细胞内在放射抗拒等。除了联合化疗和热疗外 ,联合基因治疗是一种有潜力的治疗方法
Progressive cervical cancer local radiotherapy failed mainly due to the huge primary tumor, the absolute lack of tumor dose and genetic changes lead to internal tumor cells radioresistance and so on. In addition to combination chemotherapy and hyperthermia, combined gene therapy is a potential treatment