isoniazid相关论文
Detection of the mutations in katG315 and inhA-15 of Mycobacterium tuberculosis strains isolated fro
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目的探讨结核分枝杆菌mpt64 mRNA作为结核病化疗疗效监控的细菌学分子标志物的可行性。方法2021年1月至4月，于广州市胸科医院分枝杆......
目的 利用DNA芯片检测技术直接检测痰标本中结核分枝杆菌耐利福平(RFP)、异烟肼(INH)相关的耐药基因(rpoB、katG/inhA),评价DNA芯......
目的:探讨桦褐孔菌多糖对异烟肼和利福平合用致小鼠肝损伤的保护作用.方法:48只小鼠随机分为对照组、模型组、护肝片组和桦褐孔菌......
1例30岁女性患者因肺结核给予口服利福平0.562 5 g(早餐前)和异烟肼0.4 g(晚餐后)。服药前，患者血常规及肝功能指标未见异常。服药3......
在pH 6.5的Walpole缓冲溶液中,当以300 nm的光激发时,1,2-萘醌-4-磺酸钠在468 nm处产生1个较强的荧光峰。加入异烟肼后,由于其与1,......
目的:建立HPLC法测定异烟肼维B6片中异烟肼、维生素B6含量的方法。方法:采用Agilent Eclipse Plus C18(250mm×4.6 mm,5μm)色谱柱......
维生素D(vitamin D,VD)的经典生物学作用是调节钙磷平衡,维持骨骼健康~([1])。近年的研究发现,VD3具有抗炎、抗氧化等生物学作用。......
目的评价用耐多药结核病快速诊断(GenoType MTBDRplus)试剂盒检测耐利福平、异烟肼MTB的效果。方法选取75株MTB临床分离株，采用耐多......
目的探讨抗结核药物利福平（rifampicin ，RFP ）、异烟肼 （isoniazid，INH ）、吡嗪酰胺（pyrazinamide ，PZA ）、莫西沙星（moxifloxacin ，MFX）分别与......
目的构建钛金属表面聚多巴胺、聚乙二醇、聚乳酸-聚羟基乙酸、异烟肼抗结核控释涂层，评价其表面特征、体内外释药行为、体外抑菌性......
目的探讨异烟肼所致药物性肝损伤肝组织内质网应激（ERS）蛋白葡萄糖调节蛋白78（GRP78）、生长停滞DNA损伤基因（CHOP）等的表达及双环醇对其......
Detection of the mutations in katG315 and inhA-15 of Mycobacterium tuberculosis strains isolated fro
The situation of tuberculosis and M. tuberculosis (MTB) drug resistance is severe in China. Among the MTB isolates, 27.......
Molecular characteristics of rifampin and isoniazid resistant Mycobacterium tuberculosis strains fro
Background China is one of the high burden countries of Mycobacterium tuberculosis (TB) infection globally, with high in......
在抗结核治疗策略中,异烟肼是最重要的一线药物.在过去50年的抗结核治疗中,异烟肼发挥了非常重要的作用,而耐异烟肼结核菌的出现使......
比较环丙沙星或氧氟沙星联用抗结核药的肝毒性。分别测定异烟肼组、利福平组、异烟肼利福平联合用药组及分别联用氧氟沙星或环丙沙......
目的 了解异烟肼在结核病合并慢性肝病患者中的药代动力学特点.方法 将60例结核病患者按是否合并慢性肝病分为观察组和对照组,每组......
Fast Evaluation of Oxidative DNA Damage by Liquid Chromatography-Electropray Tandem Mass Spectrometr
To establish a fast and sensitive method for the detection of 8-hydroxy-2-deoxyguanosine (8-OHdG) in precision-cut rat l......
目的 评价PMA技术检测MTB对INH耐药突变的价值,调查INH耐药突变发生特征.方法 MTB标准株H37Rv来自国家结核病参比实验室,1株INH敏......
Detection of the mutations in katG315 and inhA-15 of Mycobacterium tuberculosis strains isolated fro
The situation of tuberculosis and M. tuberculosis (MTB) drug resistance is severe in China. Among the MTB isolates, 27.8......
AIM: To evaluate the hepatoprotective effect of garlic on liver injury induced by isoniazid (INH) and rifampicin (RIF).M......
Molecular characteristics of rifampin and isoniazid resistant Mycobacterium tuberculosis strains fro
Background China is one of the high burden countries of Mycobacterium tuberculosis (TB) infection globally, with high in......
Rhabdomyolysis is one of the identified uncommon but potentially lethal complications of isoniazid intoxication, which c......
