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  5. Effect of PIPP on Phosphorylated CDC2 at Tyr15 by AKT Pathway During Meiotic Resumption of Mouse Ooc

Effect of PIPP on Phosphorylated CDC2 at Tyr15 by AKT Pathway During Meiotic Resumption of Mouse Ooc

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：LIUCHANGQI2003
【摘 要】
：
Proline-rich inositol polyphosphate 5-phosphatase(PIPP)may inhibit AKT activity by hydrolyzing the 5-phosphate of phosphatidylinositol [PtdIns(3,4,5)3] to block the interaction of PtdIns(3,4,5)3 with
【作 者】
：
Lingling Liu Gensong Li Yu Cao Xuewei Zhang Zhenha Wang Jun Zheng Bingzhi Yu Xi Deng 
【机 构】
：
The Experimental Center of the Functional Subjects,Basic Medical Scientific Research College,China M
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
proline-rich inositol polyphosphate 5-phosphatase (PIPP) protein kinase B (PKB/A 
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　　Proline-rich inositol polyphosphate 5-phosphatase(PIPP)may inhibit AKT activity by hydrolyzing the 5-phosphate of phosphatidylinositol [PtdIns(3,4,5)3] to block the interaction of PtdIns(3,4,5)3 with protein kinase B(PKB/AKT).AKT activity has been reported to promote the mitosis of fertilized mouse eggs.This investigation aimed to study the effect of PIPP on meiotic resumption in mouse oocytes.
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