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临床应用大黄,常与若干种中药以不同比例配伍,组成相对固定的药对,形成多种方剂的核心。如选取对大黄有协同、增效或辅佐作用的芒硝、枳实、厚朴,改变大黄寒凉性的附子、半夏,减轻大黄攻伐伤正的人参、甘草配伍,作了动物实验。青海省西宁生大黄(Ⅰ)与生晒参(Ⅱ)、黑附片(Ⅲ)、姜半夏(Ⅳ)、厚朴(Ⅴ)、枳实(Ⅵ)、粉甘草(Ⅶ)分别煎制的药液以及芒硝(Ⅷ)水溶液以不同比例分别配伍,经口给药,4小时溏便半数有效量为主要致泻作用指标,观察对昆明种小鼠
Clinical application of rhubarb, often with a number of kinds of traditional Chinese medicine in different proportions, forming a relatively fixed drug pairs, forming the core of a variety of prescriptions. For example, we selected the mirabilite, wolfberry, and magnolia that have synergistic, synergistic or adjuvant effects with rhubarb, and changed the cold and cool aconi, Pinellia sinensis, and reduced the compatibility of ginseng and licorice that were attacked by rhubarb. Animal experiments were conducted. Radix Dioscoreae (I) and Radix Scutellariae (II), Heishen Tablet (III), Ginger Pinellia (IV), Magnolia Officinalis (V), Fructus Citrifolia (VI), and Powdered Glycyrrhiza (VII) in Qinghai Province The liquid and Glauber’s salt (VIII) aqueous solution were mixed in different proportions and administered orally. The half effective amount for 4 hours was the main diarrhea effect indicator. Observations were made on Kunming mice.