血循环中的某些物质主要系由肝脏清除,测量这种清除能力,为肝功能提供了最敏感的、特异的和可靠的试验。对这样一种物质的清除试验系取决于肝脏的摄取、贮藏和排泄能力。清除能力可因血流变化、肝细胞功能不全或胆道系统损害而改变。曾用过外源性或内源性物质以测定肝的清除能力,但在大多数情况下,肝脏对于这些依赖它来处理的物质,到底通过什么分子机制来进行转运、细胞内结合、结合反应和排出,则仍未清楚。某种试验物质 Certain substances in the bloodstream are mainly cleared by the liver and measuring this clearance provides the most sensitive, specific, and reliable test for liver function. The clearance test for such a substance depends on the liver’s ability to take in, store and excrete. Clearance capacity may be due to changes in blood flow, liver cell dysfunction or biliary system damage and change. Exogenous or endogenous substances have been used to determine the ability of the liver to clear, but in most cases the liver relies on what molecular mechanisms it has for these substances that depend on it for transport, intracellular binding, and binding reactions And discharged, it is still not clear. Some kind of test substance