CALCINEURIN相关论文
研究一 4型心肾综合征中心肌miR-30的表达目的:确定4型心肾综合征中心肌组织miR-30表达是否出现改变方法:(1)7/8肾切除术构建大鼠4型......
Ⅰ型干扰素在抗病毒天然免疫反应中发挥着重要作用。当病毒侵染机体时,首先会被宿主的模式识别受体(Pattern recognition receptors......
心脏2型兰尼碱受体(ryanodine receptor type 2,RyR2)分布于心肌肌浆网,在兴奋收缩耦联水平调控Ca2+的释放。RyR抑制剂dantrolene最......
足细胞损伤是肾脏疾病发生发展的中心环节,足细胞是肾小球脏层上皮细胞,附于肾小球基底膜表面,是肾小球滤过屏障的重要组成,它功能......
活化T细胞核因子(NFAT)在许多免疫细胞中表达。在细胞因子基因和其它一些对免疫反应很重要的基因转录中起关键作用。NFAT蛋白活性受......
Role of the Ca2+-Calcineurin-Nuclear Factor of Activated T cell Pathway in Mitofusin-2-Mediated Immu
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The role of calcineurin in the lung fibroblasts proliferation and collagen synthesis induced by basi
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The signal transduction pathway in the proliferation of airway smooth muscle cells induced by uroten
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Calcineurin is involved in cardioprotection induced by ischemic postconditioning through attenuating
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钙调神经磷酸酶(calcineurin,CaN),是迄今所知的惟一一种受Ca^2+/钙调蛋白(calmodulin,CaM)调节的丝氨酸/苏氨酸蛋白磷酸酶。CaN广泛分布于机......
目的探讨氟对大鼠骨组织中破骨细胞的作用及其调节机制。方法将20只清洁雄性3周龄Wistar大鼠,按体重采用随机数字表法分为两组,每组1......
目的 探讨瓣膜病患者钙调神经磷酸酶-活化T细胞核因子通路(CaN-NFAT通路)与心房纤颤的关系.方法 选择因瓣膜病接受换瓣手术治疗患......
钙离子介导的信号通路(Ca2+signaling pathway)广泛地参与了真核生物中的各种生理活动过程,包括生长发育、细胞分裂、分化、程序性......
雷帕霉素(rapamycin,商品名sirolimus(R),RAP)与其它免疫抑制剂如环孢素及他克莫司等神经钙调素抑制剂(calcineurin inhibitor,CNI......
Functional repertoire of protein kinases and phosphatases in synaptic plasticity and associated neur
Protein phosphorylation and dephosphorylation are two essential and vital cellular mechanisms that regulate many recepto......
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
The role of calcineurin in the lung fibroblasts proliferation and collagen synthesis induced by basi
Objective To investigate the role of calcineurin (CaN) in the lung fibroblast proliferation and collagen synthesis indu......
Calcineurin is involved in cardioprotection induced by ischemic postconditioning through attenuating
Background Ischemic postconditioning (I-postC) is a newly discovered and more amenable cardioprotective strategy capable......
Effect of cyclosporine-A on electrophysiological properties of atria in tachycardia-induced atrial f
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Relationship of calcineurin expression between T-lymphocyte and myocardium in patients with heart fa
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Expression and unique functions of four nuclear factor of activated T cells isoforms in non-small ce
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Relationship of calcineurin expression between T-lymphocyte and myocardium in patients with heart fa
Objective Congestive heart failure (CHF) is the final common pathway of various heart diseases.Calcineurin,a calcium/cal......
Calcineurin dephosphorylates multiple serine residues near the N terminus of NFAT proteins enabling them to translocate ......
血管紧张素(1-7)是近年研究的热点之一.作为肾素-血管紧张素系统的重要组成部分,血管紧张素(1-7)与其受体Mas结合,通过调节钙调神......
Effects of metal ions on activities and solution conformations of calcineurin A subunit have been examined.The ability o......
目的探讨Wnt5a-Ca2+-CN-NFAT通路主要信号分子在正常人黑素细胞及不同黑素瘤细胞系中的激活状态。方法选取正常人原代黑素细胞(MC)......
目的 通过检测肾血管性高血压大鼠心肌肥厚过程中钙蛋白酶Ⅰ (Calpain Ⅰ)、钙调神经磷酸酶( calcineurin,CaN)、钙/钙调素依赖蛋......
Calcineurin (CN) is the only protein phosphatase known to be under the control of calcium (Ca2+) and calmodulin (CaM). T......

