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5. MAD2B Promotes Tubular Epithelial-to-Mesenchymal Transition and Renal Tubulointerstitial Fibrosis vi

MAD2B Promotes Tubular Epithelial-to-Mesenchymal Transition and Renal Tubulointerstitial Fibrosis vi

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：my_owenlin

【摘 要】

：

Background: The mitotic arrest deficient protein MAD2B is a well-defined anaphase-promoting complex/cyclosome(APC/C)inhibitor and a small subunit of DNA polymerase zeta.It is critical for mitotic cont

【作 者】

：

Hui Tang Hua Su Chun Zhang 

【机 构】

：

Department of Nephrology,Union Hospital,Tongji Medical College,Huazhong University of Science and Te

【出 处】

：

2016年国际生理学学术大会

【发表日期】

：

2016年6期

【关键词】

：

MAD2B Skp2 Tubular epithelial-to-mesenchymal transition renal tubulo-interstitia 

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　　Background: The mitotic arrest deficient protein MAD2B is a well-defined anaphase-promoting complex/cyclosome(APC/C)inhibitor and a small subunit of DNA polymerase zeta.It is critical for mitotic control and DNA repair.However,the pathological role of MAD2B in renal fibrosis has not been fully elucidated.

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